医学
防腐剂
神经外科
重症监护医学
过氧化氢
止血
外科
麻醉
病理
有机化学
化学
作者
David Bailey,Elias Rizk
出处
期刊:Neurosurgery
[Oxford University Press]
日期:2021-04-22
卷期号:89 (1): E3-E7
被引量:4
标识
DOI:10.1093/neuros/nyab107
摘要
Abstract Hydrogen peroxide (H 2 O 2 ) is a chemical with a wide range of applications. This includes its use in the medical field, in which its use has been ubiquitous but is most useful as an antiseptic and in achieving hemostasis. Neurosurgeons have been using H 2 O 2 for well over a century, primarily for its hemostatic and antiseptic effects. This is in spite of the fact that the actual effectiveness of H 2 O 2 as an antiseptic is questionable, and its use, in general, may be more dangerous than it appears. We review the application of H 2 O 2 in medicine generally and, more specifically, in neurosurgery. This review outlines the reasoning behind the use of H 2 O 2 as an antiseptic and details why it may not be as effective as one might think. We also detail its use as a hemostatic agent in neurosurgery, reviewing a number of techniques in which it has been useful in this role. Finally, we review the documented cases of complications associated with the use of H 2 O 2 in neurosurgery. Ultimately, we conclude that the use of H 2 O 2 in neurosurgery be reconsidered because of its lack of effectiveness as an antiseptic and potentially fatal complications.
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