Carboxyl-functionalized mesoporous silica-coated solid-phase microextraction Arrow for the determination of six biogenic amines in animal-derived meat

Mesoporous silica materials, SBA-15 and SBA-16, that functionalized with the carboxyl, vinyl and amino groups were synthesized in this study. The spectroscopic analysis evaluated the physicochemical characteristics of these materials. These materials were coated on the arrow-typed solid phase microextraction (SPME Arrow) to extract biogenic amines (BAs). The influences of these materials' functional groups and spatial structure on their extraction efficiency were studied. Carboxyl group modified SBA-15 (SBA-15-C) exhibited the highest extraction capacity to BAs because of the size exclusion effect and the electrostatic interaction. The extraction and desorption parameters of the SPME Arrow method were optimized. The SBA-15-C-SPME Arrow was coupled with a gas chromatography-mass spectrometry (GC-MS) system for the determination of BAs in animal-derived meat samples, which showed good repeatability (RSD<15%), satisfactory linear range (0.01–1 mg kg–1), low limit of detection (0.001–0.004 mg kg–1), and high recovery (84–129%). This method showed excellent applicability for the quantitative and qualitative detection of six BAs in animal-derived meat samples. This study provides new insight into the development of new sorbents with high extraction capacity to BAs for the selective and sensitive determination of BAs in complex meat samples.