瓦博格效应
糖酵解
乳酸脱氢酶A
厌氧糖酵解
乳酸脱氢酶
生物
癌症研究
癌症
细胞生物学
新陈代谢
生物化学
遗传学
酶
作者
Natsuski Osaka,Atsuo T. Sasaki
标识
DOI:10.1038/s42255-022-00709-3
摘要
The physiological role of aerobic glycolysis (also known as the Warburg effect), which is observed in many tumours, is still not fully understood. The finding that lactate dehydrogenase A (LDHA) activates RAC1 in breast cancer sheds new light on this persistently enigmatic aspect of cancer metabolism.
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