医学
血管免疫母细胞性T细胞淋巴瘤
单变量分析
多元分析
单变量
骨髓
内科学
总体生存率
外周T细胞淋巴瘤
肿瘤科
淋巴瘤
回顾性队列研究
T细胞
多元统计
免疫学
数学
免疫系统
统计
作者
Chen Zhang,Lan Mi,Meng Wu,Weiping Liu,Hongmei Ma,Jianli Ren,Lingfei Zhao,Chung‐I Wu,Yuqin Song,Jun Zhu
标识
DOI:10.1080/10428194.2021.2015586
摘要
Angioimmunoblastic T-cell lymphoma (AITL) is a unique sub-type of peripheral T-cell lymphoma (PTCL). We aimed to evaluate treatment programs and prognostic factors of 121 newly diagnosed patients with AITL in China from January 2001 to December 2018. The median age was 58 years with male predominance. Bone marrow involvement appeared in only 8.3% of patients, which was different from the previously published literature. The 5-year progression-free survival (PFS) and 5-year overall survival (OS) were 29.7% and 44.0%, respectively. Univariate and multivariate analyses showed that involvement of >5 nodal areas, age and Beta-2 microglubulin were highly predictive of OS but only the involvement of fewer than five nodal areas was significant for PFS. We identified a novel prognostic model including the three factors that may be applied in clinical practice and offer an alternative to IPI and PIT.
科研通智能强力驱动
Strongly Powered by AbleSci AI