甜叶菊
嵌合抗原受体
CD19
受体
抗原
生物
细胞生物学
免疫学
T细胞
遗传学
免疫系统
园艺
作者
Emine Atalay,Semiha Erişen,Mustafa Yorgancılar,Münüre Tanur
标识
DOI：10.1016/j.copbio.2011.05.445
摘要
Development of chimeric antigen receptor (CAR) T cells have led to remarkable successes in the treatment of B-cell malignancies with anti-CD19 CAR. Here we discuss the development of novel antigen receptors for use in solid malignancies with respect to target antigens, receptor design, and T cell manipulations.
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