对接(动物)
化学
计算生物学
立体化学
组合化学
生物
医学
兽医学
作者
Adukamparai Babu,R. Raghunathan,N. Mathivanan,Gurusamy Omprabhac,Devadasan Velmurugan,R.Eswaran Rangasamy
标识
DOI:10.2174/2212796810802030312
摘要
A facile synthesis and characterisation of novel dispiro-oxindolopyrrolidines is delineated. The results of the anti-microbial studies of novel dispiro-oxindolopyrrolidines are correlated with the docking calculations performed on protein S12 from 30S ribosomal subunit. Keywords: 1,3-Dipolar cycloaddition, azomethine ylide, spiro-pyrrolidines, spiro-oxindolopyrrolidine, anti-microbial activity, 30S ribosomal subunit
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