重症肌无力
医学
嗅觉系统
品味
土耳其
内科学
嗅觉
胃肠病学
心理学
神经科学
精神科
语言学
哲学
作者
Hakan Tekelı,Mehmet Güney Şenol,Aytuğ Altundağ,Esin Yalçınkaya,Mustafa Tansel Kendirli,Halit Yaşar,Murat Salihoğlu,Ömer Sağlam,Melih Çayönü,Enver Çeşmeci,Thomas Hummel
标识
DOI:10.1016/j.jns.2015.06.054
摘要
Myasthenia gravis (MG) is commonly viewed as a muscle disorder. Less is known about neurosensory function and dysfunction in MG. We aim to evaluate olfactory and gustatory behavior in Turkish patients with MG, and compare these results with age and sex-matched healthy controls.30 individuals with MG, and 30 healthy volunteers were studied. Olfactory function was studied with the Sniffin' sticks test. Taste strip test was used for studying taste function. The t-test was used for analyzing continuous variables, and the chi-square test for categorical data. Clinical staging and medication status were included in a model analyzed using analysis of variances.MG patients showed significantly lower olfactory (p<0.001) and gustatory scores (p<0.001) than the healthy controls. In addition, olfactory loss correlated with the severity of the disease. Medications for MG did not influence these results.This study replicates the olfactory dysfunction found elsewhere in MG. Further, gustatory dysfunction, an activity unrelated to muscle strength, was also unveiled. Medications used for treating MG must not be blamed for the chemosensory dysfunction found in this neurological disorder.
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