Integrated Chemical Process: One-Pot Aromatization of Cyclic Enones by the Double Elimination Methodology

A variety of aromatic hydrocarbons bearing multiple alkyl substituents are accessible with perfect regiocontrol in a one-pot reaction starting from cyclohexenones and their aromatic analogues [Eq. (1)]. The present methodology can be further extended to the synthesis of polycyclic aromatic hydrocarbons. The drawbacks encountered in the Friedel–Crafts reaction are resolved since the reaction proceeds under basic conditions.