1,5,7-Triazabicyclo[4.4.0]dec-5-ene1

[5807-14-7] C7H13N3 (MW 139.20) InChI = 1S/C7H13N3/c1-3-8-7-9-4-2-6-10(7)5-1/h1-6H2,(H,8,9) InChIKey = FVKFHMNJTHKMRX-UHFFFAOYSA-N (organic soluble very strong base for: Michael reactions,4-7 Henry reactions,8 Wittig reactions,9, 10 Horner-Wadsworth-Emmons reactions,9 transesterification reactions,10-12 etherifications,13 ring-opening polymerizations,12, 14, 15 epimerizations,19 epoxidations,20 Knoevenagel condensations,23 transamination reactions, 24, 25 deprotonation reactions,28-32 aldol reactions, Stetter reactions, trifluoromethylation reactions.) Alternate name: TBD, 2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine. Physical Data: mp 125–130 °C. Solubility: water, ethanol, acetonitrile, and most organic solvents. Form Supplied in: solid, faintly yellow, fine crystals—mostly hydrated. Handling, Storage, and Precautions: it is hygroscopic, corrosive. This reagent should be stored tightly closed under nitrogen. It is sensitive to carbon dioxide and humidity. Moderately toxic by ingestion or inhalation; skin and eye irritant.