Microfluidic Control of Fluorescence Resonance Energy Transfer: Breaking the FRET Limit

No empty FRET: The microfluidic control of fluorescence resonance energy transfer (FRET) has been demonstrated, and the FRET limit has been broken with a quantum-dot (QD)-based DNA nanosensor in a microfluidic flow. This nanosensor can detect long nucleic acids that have separation distances far beyond the range of FRET and whose detection is not feasible with conventional FRET-based assays. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z604861_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.