预期寿命
医学
不利影响
疾病
临床试验
重症监护医学
骨质疏松症
期望理论
内科学
心理学
社会心理学
环境卫生
人口
作者
J A N Dorresteijn,Lotte Kaasenbrood,Nancy R. Cook,Rob C M van Kruijsdijk,Yolanda van der Graaf,Frank L.J. Visseren,Paul M. Ridker
出处
期刊:BMJ
[BMJ]
日期:2016-03-30
卷期号:: i1548-i1548
被引量:44
摘要
Treatment effects from randomised trials are typically expressed as numbers needed to treat to prevent one adverse disease event during a fixed time interval (eg, five or 10 years). In the actual patient, however, many diseases are chronically progressive, despite treatment. Examples are diabetic nephropathy, some types of malignancies, osteoporosis, and atherosclerosis. In these examples, the aim of treatment is not to prevent but to delay the occurrence of symptomatic disease. Thus the actual effect of treatment is gain in disease-free life expectancy
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