米诺环素
酒渣鼻
医学
痤疮
皮肤病科
病因学
药品
内科学
药理学
抗生素
微生物学
生物
作者
Xianjie Yang,Minmin Kong,Huan Wang,Zhiqiang Song,Qiquan Chen
标识
DOI:10.1111/1346-8138.16779
摘要
Symptomatic dermographism (SD) is the most common form of chronic inducible urticarias. The etiology of this disease has rarely been reported in the literature. Minocycline is widely used in the treatment of acne, rosacea, and other inflammatory skin diseases. Herein we report four cases of SD onset during minocycline administration. These were young women in their 20s to 30s who were taking minocycline orally for acne vulgaris or rosacea. They all experienced the onset of SD 2-3 weeks after taking the drug, and then the complete disappearance of SD 1 month after stopping the drug. Minocycline was thought to be the culprit drug in these cases as other drugs were ruled out on clinical grounds. Our small series suggests that oral minocycline may induce SD, thus raising the awareness of this association in clinical practice. More research is needed to further confirm this association and reveal the underlying mechanism(s).
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