Prenatal PM 2.5 Exposure Induces Offspring Hypertension via Nrf2/NLRP3 Pathway

Overall, prenatal fine particulate matter exposure induces excessive inflammation and oxidative stress in paraventricular nucleus microglia through the Nrf2/NLRP3 signaling pathway, resulting in central and peripheral sympathetic overactivation, leading to hypertension and left ventricular hypertrophy.