医学
胺碘酮
心室颤动
利多卡因
自然循环恢复
心肺复苏术
室性心动过速
耐火材料(行星科学)
心脏病学
内科学
麻醉
复苏
心房颤动
天体生物学
物理
作者
George Karlis,Sevasti Afantenou
标识
DOI:10.1080/00015385.2017.1389803
摘要
Since the publication of 2000 guidelines for resuscitation, amiodarone is considered the antiarrhythmic drug of choice for refractory ventricular fibrillation/pulseless ventricular tachycardia. However, to date there is no proven benefit in terms of neurologically intact survival to hospital discharge. A comprehensive search of the recent literature on amiodarone, nifekalant and lidocaine in cardiac arrest was performed. Amiodarone and nifekalant are superior to lidocaine with regards to the return of spontaneous circulation and survival to hospital admission. Nifekalant shows a trend towards quicker termination of ventricular fibrillation compared to amiodarone. There is great uncertainty about the efficacy of antiarrhythmics in cardiac arrest. Failure to show improvements regarding meaningful survival questions their current use and suggests the need for re-evaluating their place in cardiopulmonary resuscitation.
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