Direct Reduction of Allylic Alcohols Using Isopropanol as Reductant

Abstract The lithium cation‐catalyzed direct reduction of allylic alcohols to alkenes using isopropanol as a hydride donor was developed. The hydride transfer of the in situ‐generated lithium isopropoxide to an allylic cation is the key process in this transformation. The reaction generates only water and acetone as byproducts, which highlights the synthetic utility of this method. magnified image