肝细胞癌
医学
佐剂
免疫疗法
辅助治疗
免疫系统
肿瘤科
内科学
免疫学
癌症
作者
Zachary J. Brown,Tim F. Greten,Bernd Heinrich
出处
期刊:Hepatology
[Wiley]
日期:2019-09-19
卷期号:70 (4): 1437-1442
被引量:89
摘要
Although patients undergo procedures with curative intent for early-stage hepatocellular carcinoma (HCC), up to 70% of patients may have disease recurrence in the liver at 5 years. Thus far, no therapy has proven to be effective in the adjuvant setting. Here, we discuss the application of immune-based therapies in the adjuvant setting for HCC, focusing on the underlying rationale for immunotherapies, which patients may benefit from an immune-based therapy, and what type of immune therapy should be implemented.
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