Selective synthesis of aryl thioamides and aryl-α-ketoamides from α-oxocarboxylic acids and tetraalkylthiuram disulfides: an unexpected chemoselectivity from aryl sulfonyl chlorides

Tosyl chloride-controlled generation of thioamides and α-ketoamides via base-promoted decarboxylative reaction of α-oxocarboxylic acids with tetraalkylthiuram disulfides has been established.