生物
基因
肺癌
肺鳞状细胞癌
基因组
癌症研究
癌
肿瘤科
内科学
遗传学
医学
作者
Yongheng Wang,Yimin Liu,Qianqian Wang,Fuliang Cao,Yi Guan,Yulu Chen,Binbin An,Sisi Qin,Sanqiao Yao
出处
期刊:Physiological Genomics
[American Physiological Society]
日期:2023-10-01
卷期号:55 (10): 427-439
标识
DOI:10.1152/physiolgenomics.00149.2022
摘要
Based on the differential expression of 7-methylguanosine (m 7 G) modification-associated genes between normal and lung squamous cell carcinoma (LUSC) tissues, and considering the performance of our m 7 G-related gene risk profiles as independent risk factors in predicting overall survival, we conclude that m 7 G modification is closely linked to the development of LUSC. In addition, this study offers a new genetic marker for predicting the prognosis of patients with LUSC and presents a crucial theoretical foundation for future investigations on the relationship between m 7 G modification-related genes, immunity, and drug sensitivity in LUSC.
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