Multivariate analysis of Raman spectra for discriminating human collagens: In vitro identification of extracellular matrix collagens produced by an osteosarcoma cell line

This study establishes Raman spectroscopy as a tool for identifying and characterizing human collagens, aiding in the diagnosis of connective tissue disorders. The creation of a spectral reference library for pure human collagen types I - VI holds potential for medical diagnostics, analytical chemistry, and materials science applications.