An Insight into Diverse Activities and Targets of Flavonoids

植物化学 多酚 传统医学 计算生物学 类黄酮 抗氧化剂 生物 医学 生物化学
作者
Rakhi Mishra,Prashant Tiwari,Avijit Mazumder,Rupa Mazumder,Ayushi Singh
出处
期刊:Current Drug Targets [Bentham Science Publishers]
卷期号:24 (1): 89-102 被引量:8
标识
DOI:10.2174/1389450123666220915121236
摘要

Background: Flavonoids belong to the chemical class of polyphenols and are in the cate- gory of secondary metabolites imparting a wide protective effect against acute and chronic diseases. Objective: The study aims to investigate and summarize the information of various flavonoids ex-tracted, isolated from various sources, and possess different pharmacological properties by acting on multiple targets. Methods:: This comprehensive review summarizes the research information related to flavonoids and their pharmacological action targets from various sources like PubMed, Google Scholar and Google websites. Result: Extracted information in the paper discusses various therapeutic effects of flavonoids iso-lated from medicinal plant sources, which have the property to inhibit several enzymes, which final-ly results in health benefits like anti-cancer, anti-bacterial, antioxidant, anti-allergic, and anti-viral effects. This study also showed the different solvents and methods involved in the extraction and characterization of the isolated phytochemical constituents. Conclusion: The findings showed the contribution of several flavonoids in the management and in-hibition of various acute and chronic sicknesses by acting on different sites in the body. This study may lead to gaining interest for more research on the bioactives of different medicinal plants for the discovery of new lead compounds or further improvement of the efficacy of the existing compound.

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