Towards continuous Rh-hydroformylation of long chain alkenes: Handling methodology for the long-term stability of Biphephos in a continuous reactor with an attached membrane separation unit

Diphosphites like Biphephos are known for their combination of high activity and high linear selectivity in the Rh-catalyzed hydroformylation of terminal alkenes. However, like most phosphite-type ligands, Biphephos is prone...