医学
间质性肺病
鉴定(生物学)
疾病
结缔组织病
结缔组织
内科学
重症监护医学
病理
肺
自身免疫性疾病
植物
生物
作者
Masataka Kuwana,Masashi Bando,Yutaka Kawahito,Shinji Sato,Takafumi Suda,Yasuhiro Kondoh
标识
DOI:10.1080/17476348.2023.2176303
摘要
Background Interstitial lung disease (ILD) is a common complication of connective tissue diseases (CTD), but there are few clinical trials to guide disease management. We aimed to develop expert consensus statements and an algorithm for CTD-ILD management.Research design and methods Based on a targeted literature review, we developed 109 statements on managing CTD-ILD across six domains. We used a modified Delphi process to survey 22 physicians in Japan involved in managing CTD-ILD (specialists in pulmonology, rheumatology, pathology, and radiology). These panelists participated in two rounds of web-based survey to establish consensus statements, which were used to define an algorithm. Consensus was defined as a mean value ≥70 on a scale of 0 (strong disagreement) to 100 (strong agreement).Results Between May–August 2022, consensus was reached on 93 statements on CTD-ILD management. The most important consensus statements included screening CTD patients for ILD (typically with high-resolution computed tomography), using imaging, pulmonary function testing and serum biomarkers for diagnosis and severity assessment, regularly following up patients, and multidisciplinary management of CTD-ILD. Consensus statements were interpreted into an algorithm for clinical guidance.Conclusions Using the Delphi process, we have developed consensus statements and an algorithm to guide clinical decision-making for CTD-ILD.
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