再现性
迭代重建
图像质量
无线电技术
人工智能
计算机科学
噪音(视频)
算法
重建算法
一致相关系数
图像(数学)
计算机断层摄影术
模式识别(心理学)
数学
医学
放射科
统计
作者
Baiyu Yang,Xinyuan Chen,Siqi Yuan,Yuxiang Liu,Jianrong Dai,Kuo Men
标识
DOI:10.1016/j.radonc.2022.02.034
摘要
Hybrid iterative reconstruction (HIR) is the most commonly used algorithm for four-dimensional computed tomography (4DCT) reconstruction due to its high speed. However, the image quality is worse than that of model-based iterative reconstruction (MIR). Different reconstruction methods affect the stability of radiomics features. Herein, we developed a deep learning method to improve the quality and radiomics reproducibility of the high-speed reconstruction.The 4DCT images of 70 patients were reconstructed using both the HIR and MIR algorithms. A cycle-consistent adversarial network was adopted to learn the mapping from HIR to MIR, and then generate synthetic MIR (sMIR) images from HIR. The performance was evaluated using the testing set (10 patients).The total reconstruction times for the HIR, MIR, and proposed sMIR images were approximately 2.5, 15, and 3.1 mins, respectively. The quality of sMIR images was close to that of MIR and was superior to that of HIR images, with noise reduced by 45-77% and contrast-to-noise ratio improved by 91-296%. The concordance correlation coefficients (CCC) of radiomic features improved from 0.89 ± 0.15 for HIR to 0.97 ± 0.07 for the proposed sMIR. The percentage of reproducible features (CCC ≥ 0.85) increased from 76.08% for HIR to 95.86% for sMIR, with an improvement of 19.78%.Compared to existing HIR algorithm, the proposed method improves the image quality and radiomics reproducibility of 4DCT images under high-speed reconstruction. It is computationally efficient and has potential to be integrated into any CT system.
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