品味
味觉感受器
舌头
神经科学
受体
电池类型
生物
细胞生物学
解剖
化学
细胞
生物化学
医学
病理
作者
Heather N. Turner,Emily R. Liman
出处
期刊:Annual Review of Physiology
[Annual Reviews]
日期:2022-02-10
卷期号:84 (1): 41-58
被引量:12
标识
DOI:10.1146/annurev-physiol-060121-041637
摘要
Sour taste, the taste of acids, is one of the most enigmatic of the five basic taste qualities; its function is unclear and its receptor was until recently unknown. Sour tastes are transduced in taste buds on the tongue and palate epithelium by a subset of taste receptor cells, known as type III cells. Type III cells express a number of unique markers, which allow for their identification and manipulation. These cells respond to acid stimuli with action potentials and release neurotransmitters onto afferent nerve fibers, with cell bodies in geniculate and petrosal ganglia. Here, we review classical studies of sour taste leading up to the identification of the sour receptor as the proton channel OTOP1.
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