Thiol-Lactam Initiated Radical Polymerization (TLIRP): Scope and Application for the Surface Functionalization of Nanoparticles

: Controlled polymerization techniques make the possible fabrication of polymers with desired molecular weights, narrow dispersity, and tailor-making of advanced hybrid materials. Thiol- Lactam Initiated Radical Polymerization (TLIRP) was introduced in 2002 and developed during the last two decades. The thiol/lactam combination enables one to generate radicals that can initiate the polymerization of vinyl-based monomers. The study of the mechanism and kinetics of TLIRP revealed the characteristics of living polymerization for TLIRP. Moreover, TLIRP has been used successfully for the synthesis of homopolymers, block copolymers, and statistical copolymers with polydispersity below 2.0. Especially, TLIRP provides a very straightforward method for grafting polymer brushes on the surface of nanoparticles. We review herein the systems developed for TLIRP and their applications for macromolecular engineering, emphasizing the surface functionalization of nanoparticles via the grafting-from approach.