Initial management for acute lower gastrointestinal bleeding

医学 结肠镜检查 便血 下消化道出血 止血 阿司匹林 放射科 外科 内科学 结直肠癌 癌症
作者
Tomonori Aoki,Yoshihiro Hirata,Atsuo Yamada,Kazuhiko Koike
出处
期刊:World Journal of Gastroenterology [Baishideng Publishing Group]
卷期号:25 (1): 69-84 被引量:69
标识
DOI:10.3748/wjg.v25.i1.69
摘要

Acute lower gastrointestinal bleeding (LGIB) is a common indication for hospital admission.Patients with LGIB often experience persistent or recurrent bleeding and require blood transfusions and interventions, such as colonoscopic, radiological, and surgical treatments.Appropriate decision-making is needed to initially manage acute LGIB, including emergency hospitalization, timing of colonoscopy, and medication use.In this literature review, we summarize the evidence for initial management of acute LGIB.Assessing various clinical factors, including comorbidities, medication use, presenting symptoms, vital signs, and laboratory data is useful for risk stratification of severe LGIB, and for discriminating upper gastrointestinal bleeding.Early timing of colonoscopy had the possibility of improving identification of the bleeding source, and the rate of endoscopic intervention, compared with elective colonoscopy.Contrast-enhanced computed tomography before colonoscopy may help identify stigmata of recent hemorrhage on colonoscopy, particularly in patients who can be examined immediately after the last hematochezia.How to deal with nonsteroidal antiinflammatory drugs (NSAIDs) and antithrombotic agents after hemostasis should be carefully considered because of the risk of rebleeding and thromboembolic events.In general, aspirin as primary prophylaxis for cardiovascular events and NSAIDs were suggested to be discontinued after LGIB.Managing acute LGIB based on this information would improve clinical outcomes.Further investigations are needed to distinguish patients with LGIB who require early colonoscopy and hemostatic intervention.

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