急性胰腺炎
医学
胰腺炎
重症监护医学
临床试验
内科学
作者
Jiao Jiang,Shu Huang,Huifang Xia,Kang Zou,Xinyi Zeng,Han Zhang,Chunyu Zhong,Shali Tan,Yan Peng,Muhan Lü,Xiaowei Tang
出处
期刊:Pancreas
[Ovid Technologies (Wolters Kluwer)]
日期:2022-07-14
卷期号:51 (5): 445-451
标识
DOI:10.1097/mpa.0000000000002051
摘要
Clinical studies are important in informing evidence-based practice for patients with acute pancreatitis (AP). To determine whether registered studies adequately meet this need, we leveraged the ClinicalTrials.gov database to provide an overview of studies pertaining to AP.ClinicalTrials.gov was searched and the search term used was AP. Analysis was restricted to studies registered before January 12, 2021.Of 363,632 trials overall, 234 (0.06%) were eventually included for analysis. Interventional studies and observational studies comprised 67.5% and 32.5% of these studies respectively. Most studies were initiated 2007 or later. Endoscopic retrograde cholangiopancreatography was the single most frequent cause of AP specified in these studies (16.7%). Nearly 72% of these studies had a sample size greater than 50. With respect to study design, 87.3% of interventional studies were randomized, 53.5% were blinded. The top 3 countries with the largest number of registered studies were China (n = 59), followed by the United States (n = 53) and India (n = 12).Our results indicate that the research activity falls short of what is needed in terms of the burden of AP. The distribution of these AP-related studies by global regions indicates that there exists regional disparities.
科研通智能强力驱动
Strongly Powered by AbleSci AI