冈比亚按蚊
迪特
酮
碳链
化学
立体化学
按蚊
疟疾
药物化学
有机化学
毒理
生物
免疫学
作者
Ester Innocent,N K Gikonyo,M H Nkunya
出处
期刊:Tanzania health research bulletin
[African Journals Online]
日期:2008-04-16
卷期号:10 (1)
被引量:41
标识
DOI:10.4314/thrb.v10i1.14342
摘要
Long chain aliphatic methyl ketone series of C 7 -C 15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s.All methyl ketones produced a dose dependent (P<0.001)repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations.Aliphatic methyl ketones of C 7 -C 10 had lower activity than those of C 11 -C 15.However, within this range compounds with odd carbon atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2-dodecanone).Comparable repellency activity of 2-tridecanone to DEET show that, it may save as Anopheles gambiae s.s.mosquito repellent.
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