作者
Babatunde Oluwafemi Adetuyi,Pere-Ebi Yabrade Toloyai,Peace Abiodun Olajide,Oluwakemi Semiloore Omowumi,Charles Oluwaseun Adetunji,Osarenkhoe Omorefosa Osemwegie,Mohammed Bello Yerima,Juliana Bunmi Adetunji,M.L. Attanda,Olatunji Matthew Kolawole,Abel Inobeme,Oluwabukola Atinuke Popoola
摘要
Bacterial, fungal, and viral pathogens are the leading causes of life-threatening illnesses and deaths worldwide. Antibiotics and other antimicrobial medicines have seen widespread use for the treatment of illnesses because of their remarkable efficacy. Unfortunately, the widespread use of these medications has contributed to the spread of bacteria, fungi, viruses, and parasites that are resistant to a wide variety of antimicrobial treatments. The appearance of new irresistible diseases, basic diseases, and the production of biofilms present a more formidable challenge to the established therapy line because of the human immune system’s natural resistance to antibacterial medications. A novel, incomplete, and imaginative supply of antibacterial, antiviral, antifungal, and antiparasitic compounds can be found in rejuvenating ointments (EOs), which are made up of fundamentally and naturally distinct components. However, because of their unpredictability, antipathy toward synthetics, and limited solubility, they are unable to fully realize their antibacterial potential. To get over these restrictions, scientists have been looking into nanoparticles made from biodegradable polymeric and inorganic materials. Nanomaterials are currently researched as lipid nanoparticles for antibacterial distribution, antibacterial films for processed foods, surgical implants, and therapeutic components in wound dressing and storage containers because they have the ability to counteract bacterium resistance on their own. Only a few of the potential advantages of essential oil-loaded nanoparticles include synergy in antibacterial activity, increased dissolution, lower volatility, chemical inertness, sustained release, and storage stability. To increase their antimicrobial activity, medicinal oils, and their constituents could be used in a variety of contexts, from food safety and packaging to alternative treatments for drug-resistant illnesses, and these contexts are discussed in this article.