心理学
认知
临床心理学
背景(考古学)
自杀意念
慢性应激
神经认知
适度
认知脆弱性
认知灵活性
毒物控制
医学
精神科
自杀预防
抑郁症状
环境卫生
神经科学
古生物学
社会心理学
生物
作者
Shayna M. Cheek,Anastacia Y. Kudinova,Eva Kuzyk,David B. Goldston,Richard T. Liu
标识
DOI:10.1016/j.jad.2023.07.075
摘要
Cognitive inflexibility has recently been investigated as potential vulnerability factor for suicidal ideation (SI), but the context in which it may convey risk is unclear. Life stress has also been reliably associated with SI among adolescents, and following a stress-diathesis model, may be a factor that moderates the relationship between cognitive inflexibility and SI. Psychiatrically hospitalized adolescents (N = 259) at high risk for future SI were followed for 18 months after discharge. Interviews assessing life stress and SI and a neurocognitive task assessing cognitive inflexibility were conducted at six- and 12-months. SI was also assessed at 18-month post-discharge. Linear mixed models were used to determine the moderating effect of stress on the relationship between cognitive inflexibility and SI, accounting for relevant clinical and demographic covariates. Chronic stress moderated the association between cognitive inflexibility and SI, with a stronger association found among youth with greater levels compared to lower levels of chronic stress. This finding was maintained after statistically adjusting for depressive symptoms and relevant demographic covariates. No prospective associations between cognitive inflexibility, life stress, and SI were found. SI was measured at 6-month intervals, precluding evaluation of the relationship on a more proximal timescale. Cognitively inflexible adolescents under conditions of high chronic stress are more likely to experience increased SI severity, supporting a cognitive inflexibility stress-diathesis model of SI in adolescents. The findings highlight the importance of assessing these modifiable factors among adolescents at a high risk for SI.
科研通智能强力驱动
Strongly Powered by AbleSci AI