医学
危险系数
四分位数
比例危险模型
坐
全国健康与营养检查调查
生物统计学
流行病学
队列研究
队列
前瞻性队列研究
人口学
全国死亡指数
置信区间
环境卫生
内科学
人口
病理
社会学
作者
Huimin Zhou,Jun Nie,Yanmei Cao,L. Y. Diao,Xiaoli Zhang,Jiafu Li,Siyu Chen,Xu Zhang,Guo‐Chong Chen,Zengli Zhang,Bingyan Li
标识
DOI:10.1186/s12889-024-18515-9
摘要
Abstract Background Sedentary behavior has been demonstrated to be a modifiable factor for several chronic diseases, while coffee consumption is believed to be beneficial for health. However, the joint associations of daily sitting time and coffee consumption with mortality remains poorly understood. This study aimed to evaluate the independent and joint associations of daily sitting time and coffee intakes with mortality from all-cause and cardiovascular disease (CVD) among US adults. Methods An analysis of a prospective cohort from the 2007–2018 National Health and Nutrition Examination Survey of US adults ( n = 10,639). Data on mortality were compiled from interview and physical examination data until December 31, 2019. Daily sitting time was self-reported. Coffee beverages were from the 24-hour diet recall interview. The main outcomes of the study were all-cause and cardiovascular disease mortality. The adjusted hazard ratios [HRs] and 95% confidence intervals [CI] were imputed by Cox proportional hazards regression. Results Among 10,639 participants in the study cohort, there were 945 deaths, 284 of whom died of CVD during the follow-up period of up to 13 years. Multivariable models showed that sitting more than 8 h/d was associated with higher risks of all-cause (HR, 1.46; 95% CI, 1.17–1.81) and CVD (HR, 1.79; 95% CI, 1.21–2.66) mortality, compared with those sitting for less than 4 h/d. People with the highest quartile of coffee consumption were observed for the reduced risks of both all-cause (HR, 0.67; 95% CI, 0.54–0.84) and CVD (HR, 0.46; 95% CI, 0.30–0.69) mortality compared with non-coffee consumers. Notably, joint analyses firstly showed that non-coffee drinkers who sat six hours or more per day were 1.58 (95% CI, 1.25–1.99) times more likely to die of all causes than coffee drinkers sitting for less than six hours per day, indicating that the association of sedentary with increased mortality was only observed among adults with no coffee consumption but not among those who had coffee intake. Conclusions This study identified that sedentary behavior for more than 6 h/d accompanied with non-coffee consumption, were strongly associated with the increased risk of mortality from all-cause and CVD.
科研通智能强力驱动
Strongly Powered by AbleSci AI