医学
克拉斯
养生
内科学
胃肠病学
联合疗法
临床终点
卵巢癌
肿瘤科
癌症
外科
临床试验
结直肠癌
作者
Susana Banerjee,Els Van Nieuwenhuysen,Carol Aghajanian,Véronique D’Hondt,Bradley J. Monk,Andrew R. Clamp,Emily Prendergast,Ana Oaknin,Kari L. Ring,Nicoletta Colombo,Robert W. Holloway,Manuel Rodrigues,Hye Sook Chon,Charlie Gourley,Alessandro D. Santin,Premal H. Thaker,Christine Gennigens,Gregg Newman,E. Salinas,Hagop Youssoufian
摘要
The efficacy and safety profile of avutometinib in combination with defactinib support this combination as a potential standard of care for recurrent LGSOC. A randomized phase 3 study of avutometinib and defactinib versus investigator's choice of therapy for women with recurrent LGSOC is currently enrolling (RAMP301; ClinicalTrials.gov identifier: NCT06072781).
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(2025-6-4)
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