Fecal metabolites reflecting the interaction between prebiotic dietary fiber and the gut microbiota in obese patients

Rationale: Inulin-type fructans (ITF) are dietary prebiotic fibers that may confer beneficial health effects through changes in the gut microbiota. The identification of potential mediators brings us closer to a mechanistic understanding of how prebiotics work. The project FiberTAG1 aims to establish a set of markers of gut barrier function and bacterial metabolites, linking dietary fiber intake to gut microbiota-related health effects. We have tested the impact of native inulin intervention on fecal metabolites characterizing the interaction gut microbiota-related health effects in obese patients.