脑电图
非快速眼动睡眠
多导睡眠图
重性抑郁障碍
听力学
心理学
睡眠(系统调用)
慢波睡眠
K-络合物
睡眠阶段
睡眠开始
失眠症
内科学
精神科
医学
认知
操作系统
计算机科学
作者
Seung-Gul Kang,Sara Mariani,Stephanie A. Marvin,Kwang Pil Ko,Susan Redline,John W. Winkelman
标识
DOI:10.1016/j.pnpbp.2018.04.010
摘要
We aimed to identify the sleep electroencephalography (EEG) spectral power correlates of the subjective-objective discrepancy (SOD) of sleep onset latency (SOL) in major depressive disorder (MDD), primary insomnia (PI), and normal sleeping control (NSC) groups. We examined relative power values in standard frequency bands of the EEG spectra during the first Non-Rapid Eye Movement (NREM) sleep period as correlates of SOD of SOL between sleep diary and polysomnography in MDD (n = 36), PI (n = 19), and NSC (n = 23) groups. We also compared the relative spectral power of sleep EEG among MDD (n = 40), PI (n = 19), and NSC (n = 23) groups. SOD of SOL in MDD patients was positively correlated with relative sigma (r = 0.622, p corrected < 0.001), beta power (r = 0.559, p corrected = 0.002), and alpha power (r = 0.469, p corrected = 0.024) in the first NREM sleep period. There was no significant difference of sleep EEG power spectra among the three groups. SOD was positively correlated with high frequency EEG in MDD. High frequency EEG power is thought to be associated with hyperarousal and memory consolidation, and future larger-scale studies may further elucidate the neurophysiological mechanisms underlying SOD of sleep onset duration.
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