坐骨神经痛
医学
无菌处理
微生物培养
外科
椎间盘
污染
无氧运动
细菌
生理学
腰椎
生态学
遗传学
生物
作者
Peleg Ben‐Galim,Nahshon Rand,Michael Giladi,David R. Schwartz,Ely Ashkenazi,Michael Millgram,S. Dekel,Yizhar Floman
出处
期刊:Spine
[Ovid Technologies (Wolters Kluwer)]
日期:2006-10-01
卷期号:31 (21): 2507-2509
被引量:51
标识
DOI:10.1097/01.brs.0000238657.13263.b2
摘要
Discs were cultured during discectomy from patients with back pain, sciatica, and radiologic evidence of disc herniation causing nerve root compression.To investigate the claim of culpability of bacteria in causing the local inflammatory process seen in patients with disc herniation and radiculopathy.Bacteria have been cultured from intervertebral discs of patients with sciatica. An infectious etiology for sciatica could have a dramatic effect on treatment options for this common problem.To minimize the risk of contamination, the surgeon performed processing and culturing procedures intraoperatively under stringent sterile conditions. Immediately following disc excision, the specimens were divided into 4 pieces, and cultured in various aerobic and anaerobic culture mediums that were incubated for 2 weeks.The 120 specimens from 30 patients underwent bacterial culture growth: 116 were sterile, an 4 aerobic cultures (2 patients) grew coagulase-negative staphylococci, suggestive of contamination.These results refute the hypothesis that microbial infection plays a role in the pathogenesis of sciatica. It is possible that bacterial growth from discs reported in previous studies was at least partly related to contamination, which we painstakingly avoided by application of rigorous aseptic techniques.
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