医学
狼疮性肾炎
内科学
抗dsDNA抗体
胃肠病学
抗体
系统性红斑狼疮
肾炎
免疫学
红斑狼疮
补体C1q
疾病
补体系统
作者
Ana‐Maria Orbai,Lennart Truedsson,Gunnar Sturfelt,Ola Nived,Hong Fang,Graciela S. Alarcón,Caroline Gordon,JT Merrill,Paul R. Fortin,Ian N Bruce,David Isenberg,Daniel J. Wallace,Rosalind Ramsey‐Goldman,Sang‐Cheol Bae,John G. Hanly,Jorge Sánchez‐Guerrero,Ann E. Clarke,Cynthia Aranow,S Manzi,Murray B. Urowitz
出处
期刊：Lupus
[SAGE Publishing]
日期：2014-08-14
卷期号：24 (1): 42-49
被引量：110
标识
DOI：10.1177/0961203314547791
摘要
Anti-C1q was more common in patients with SLE and those of Asian race/ethnicity. We confirmed a significant association of anti-C1q with renal involvement, independent of demographics and other serologies. Anti-C1q in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis.
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