Chinese Medicine Prescription Recommendation Using Generative Adversarial Network

药方 计算机科学 生成语法 人工智能 人工神经网络 对抗制 隐马尔可夫模型 深度学习 序列(生物学) 机器学习 医学 生物 药理学 遗传学
作者
Chuitian Rong,Xueyan Li,Xuemei Sun,Huabo Sun
出处
期刊:IEEE Access [Institute of Electrical and Electronics Engineers]
卷期号:10: 12219-12228 被引量:13
标识
DOI:10.1109/access.2022.3143797
摘要

The theory of traditional Chinese medicine (TCM) is an important part of Chinese culture. In the long history, there are a large number of excellent prescriptions, whose laws have been explored by many studies, but few works directly studied the generation of prescriptions. With the rapid development of deep learning, many applications of text generation using neural networks have emerged. Prescriptions are the doctors’ clinical experience and the results of neural networks also come from the accumulated experience. So, it is very feasible to apply deep learning techniques to the recommendation on TCM prescriptions. GAN and its variants have been applied in text generation recently. It has advantages in many aspects, such as the rapid speed of computation, the update of parameters by back propagation without Markov chain and more real data generation with two-players game. We attempted to know the important attributes of prescriptions and use these contents as the training data for variants of GAN to generate prescriptions. Specifically, we attempted to apply SeqGAN (Sequence Generative Adversarial Nets) and CGAN (Conditional Generative Adversarial Nets) to prescription generations. By underlying the knowledge of TCM, the prescriptions with different characteristics can be successfully generated. In the experiments, we conducted the comparative evaluations on the original data with other models. The results showed that applications in the innovation of prescription sequence generations have certain feasibility and significance, even can provide some reference values for the innovation of TCM.
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