医学
认知功能衰退
队列
疾病
认知
内科学
队列研究
生物标志物
老年学
纵向研究
干预（咨询）
认知障碍
肿瘤科
纵向数据
前瞻性队列研究
比例危险模型
流行病学
作者
Calvin Trieu,Argonde C. van Harten,Mardou S. S. A. van Leeuwenstijn,Lisa‐Marie Schlüter,Lynn Boonkamp,Azzam Aladdin,Sietske A.M. Sikkes,Elsmarieke van de Giessen,Inge M.W. Verberk,Charlotte E. Teunissen,Wiesje M. van der Flier
出处
期刊：JAMA network open
[American Medical Association]
日期：2025-12-03
卷期号：8 (12): e2545862-e2545862
被引量：3
标识
DOI：10.1001/jamanetworkopen.2025.45862
摘要
This cohort study of individuals with SCD suggests that longitudinal plasma pTau217 and GFAP are suitable biomarkers for monitoring AD pathology. Their changes were associated with cognitive decline and clinical progression, supporting their potential utility for early intervention and disease monitoring.
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(2025-6-4)
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