Albumin: Biochemical properties and therapeutic potential†

Properties of AlbuminLigand-Binding.HSA binds many endogenous and exogenous compounds, including fatty acids, metal ions, pharmaceuticals, and metabolites, with implications for drug delivery and efficacy, detoxification, and antioxidant protection.Several low-and high-affinity ligand-binding sites have been identified on HSA, the first of which to be identified (termed site I and II) are responsible for the binding of most pharmaceuticals that interact with the protein.Sites I and II are located in different domains and