急性肾损伤
临床实习
重症监护医学
围手术期
预测能力
审查
医学
预测建模
预测值
医疗保健
质量(理念)
风险分析(工程)
计算机科学
内科学
外科
物理疗法
机器学习
哲学
认识论
经济增长
政治学
法学
经济
标识
DOI:10.1016/j.bja.2024.05.013
摘要
The increased availability of large clinical datasets together with increasingly sophisticated computing power has facilitated development of numerous risk prediction models for various adverse perioperative outcomes, including acute kidney injury (AKI). The rationale for developing such models is straightforward. However, despite numerous purported benefits, the uptake of preoperative prediction models into clinical practice has been limited. Barriers to implementation of predictive models, including limitations in their discrimination and accuracy, as well as their ability to meaningfully impact clinical practice and patient outcomes, are increasingly recognised. Some of the purported benefits of predictive modelling, particularly when applied to postoperative AKI, might not fare well under detailed scrutiny. Future research should address existing limitations and seek to demonstrate both benefit to patients and value to healthcare systems from implementation of these models in clinical practice.
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