In Sequence Anti-Fibrotic Treatment and Rehabilitation following Volumetric Muscle Loss Injury

Mitigation of local pathologic fibrotic tissue deposition is a target area of interest for volumetric muscle loss (VML); nintedanib has shown promise for reduction of fibrosis following VML. Herein studies investigate how in sequence anti-fibrotic treatment administered immediately following VML and delayed rehabilitation could improve functional recovery after VML.