Recent advances in the chemistry and the application of SF5-compounds

Abstract This review article outlines the literature from 2022 to 2024 covering developments in SF5 chemistry. Recent synthetic methodologies of SF5-containing building blocks are reported. These methods include the synthesis of SF5Cl and its use in pentafluorosulfanylation reactions and oxidative fluorination reactions. Moreover, the reactivity of SF5-alkynes as versatile platform to access new SF5-compounds is described. Finally, the effects of the SF5 moiety are highlighted according to its application in different fields, such as biological/medicinal chemistry, catalysis, and material sciences. 1 Introduction 2 Access to SF5-Containing Building Blocks 2.1 By Means of SF5Cl 2.1.1 Generation of SF5Cl 2.2 By Means of Oxidative Fluorination 2.3 By Means of SF5-Alkynes 2.4 Other Miscellaneous Aromatic and Aliphatic SF5-Compounds 3 Applications 3.1 Medicinal and Biological Chemistry 3.2 Material Science 3.3 Catalysis 4 Conclusion