医学
内科学
前瞻性队列研究
急性冠脉综合征
比例危险模型
经皮冠状动脉介入治疗
队列
胃肠病学
心脏病学
肿瘤科
心肌梗塞
作者
Xiaoxiao Zhao,Jiannan Li,Runzhen Chen,Nan Li,Linghan Xue,Shaodi Yan,Chen Liu,Peng Zhou,Yi Chen,Hongbing Yan,Yu Guang Tan,Hanjun Zhao,Li Song
标识
DOI:10.1186/s12933-025-02877-4
摘要
These findings establish AIP as a critical modifier of CHIP-related cardiovascular risk, potentially through enhanced inflammatory pathways in younger ACS populations. The study highlights the clinical utility of combining lipid-based (AIP) and genetic (CHIP) biomarkers for precision prognostication, though validation in larger cohorts and mechanistic investigations of the AIP-CHIP interplay are warranted to guide targeted therapies.
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