A ratiometric electrochemical sensor for detecting lead in fish based on the synergy of semi-complementary aptamer pairs and Ag nanowires@zeolitic imidazolate framework-8

This sensor uses I Fc as the conformation change signals and I MB as the internal reference signal. AgNWs@ZIF-8 is used to generate an internal reference signal. The sensor shows a range of 20 nM to 9 μM with a detection limit of 10 nM (S/N = 3).