化学
分光光度法
生化工程
药品
药物
杂质
纳米技术
制药工业
剂型
药物发现
组合化学
色谱法
工艺工程
有机化学
药理学
材料科学
工程类
医学
生物化学
作者
Avvaru Praveen Kumar,Deepak Kumar
出处
期刊:Current Pharmaceutical Analysis
[Bentham Science]
日期:2021-07-28
卷期号:17 (9): 1156-1170
被引量:8
标识
DOI:10.2174/1573412917999200909144354
摘要
Pharmaceuticals are the chemical molecules which were invented to improve the life of living things through diagnosing, curing, treating, or preventing diseases. Pharmaceuticals can do their maximum function or work against disease or prevent from harmful effects of diseases only if they are free from impurities. The pharmaceutical analysis consists of different essential and important procedures to ascertain “identity, strength, quality and purity” of drug molecules. There are three different possibilities to originate impurities, which include (i) at the developmental stages of pharmaceuticals, (ii) at the time of transportation, and (iii) storage conditions. Therefore, the pharmaceuticals must be examined at all stages and the impurities should be discovered and quantified. The pharmaceutical analysis also admits that the analysis of intermediates and raw materials during the synthesis of drug molecules. Instrumentation is required to perform pharmaceutical analysis and methods can be developed to certain required levels. This review affords the basic theory of UV-Visible spectrophotometry and its applications, pharmaceutical method development and validation, and a list of some reported spectrophotometric methods, which are employed in pharmaceutical analysis from 2011 to 2020.
科研通智能强力驱动
Strongly Powered by AbleSci AI