Local recurrence and other oncologic outcomes after percutaneous image-guided tumor ablations on stageT1b renal cell carcinoma: a systematic review and network meta-analysis

医学 低温消融 肾细胞癌 微波消融 经皮 临床终点 不利影响 肾癌 射频消融术 烧蚀 荟萃分析 临床试验 外科 随机对照试验 放射科 肿瘤科 内科学
作者
Grégoire Cazalas,E. Jambon,Alexis Coussy,Yann Le Bras,François Petitpierre,Jean Christophe Berhnard,Nicolas Grenier,C. Marcelin
出处
期刊:International Journal of Hyperthermia [Taylor & Francis]
卷期号:38 (1): 1295-1303 被引量:3
标识
DOI:10.1080/02656736.2021.1970826
摘要

Objective A systematic review of clinical trials on thermal ablation of T1b RCC was conducted to assess oncologic outcomes of those procedures. The primary endpoint was the rate of local recurrence. Secondary endpoints included technical efficacy, progression to metastatic disease, cancer-specific mortality, complications and renal function decrease. Methods PubMed (MEDLINE) and Embase databases were searched in June 2020 for eligible trials following the PRISMA selection process. Prevalence of local recurrence and per procedural major adverse effects were calculated using double arcsine transformation and a random-effects model. Results Nine clinical trials (all retrospective) involving 288 patients with T1b renal clear cell carcinoma treated with either percutaneous microwave ablation, cryoablation or radiofrequency ablation were analyzed. Using a random-effects model, the overall prevalence of local recurrence following percutaneous ablation was 0.08 (0.04-0.14; p = 0.05). Primary technical efficacy was 226/263 (86%) patients and secondary technical efficacy was 247/263 (94%). Overall, 10/176 (6%) patients presented metastatic locations following the ablation. Major adverse effects prevalence was 0.09 (0.06-0.14; p = 0.05). Conclusions Thermal ablations are feasible, safe, and effective to treat T1b renal clear cell carcinoma. More trials are necessary to determine the rate of the evidence of the benefit.HighlightsThermal ablations are feasible and safe to treat T1b renal clear cell carcinoma.Oncologic outcomes appear to be very good on both local control and distant progression.Due to small number and heterogeneity of studies more trials are necessary to determine the rate of the evidence of the benefit.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
纷纭完成签到,获得积分10
1秒前
1秒前
1秒前
2秒前
kehe!完成签到 ,获得积分0
2秒前
蔡蔡蔡发布了新的文献求助10
5秒前
引子完成签到,获得积分10
5秒前
庄海棠完成签到 ,获得积分10
6秒前
点点滴滴发布了新的文献求助10
7秒前
hhhhhh发布了新的文献求助10
8秒前
阔达的铅笔完成签到,获得积分10
8秒前
9秒前
苗条白枫完成签到 ,获得积分10
10秒前
冉冉完成签到 ,获得积分0
10秒前
机灵的鲜花完成签到 ,获得积分10
12秒前
点点滴滴完成签到,获得积分20
12秒前
12秒前
九零后无心完成签到,获得积分10
16秒前
爆米花应助靖哥哥采纳,获得30
17秒前
独行侠完成签到,获得积分10
17秒前
外向钢笔发布了新的文献求助10
18秒前
hhhhhh完成签到,获得积分20
18秒前
华仔应助点点滴滴采纳,获得10
19秒前
完美的沉鱼完成签到 ,获得积分10
19秒前
嗨Honey完成签到 ,获得积分10
20秒前
成成完成签到,获得积分0
20秒前
追梦发布了新的文献求助10
20秒前
22秒前
25秒前
25秒前
25秒前
飞速get完成签到 ,获得积分10
26秒前
科研通AI5应助单纯的手机采纳,获得10
26秒前
26秒前
普萘没有洛尔完成签到 ,获得积分10
26秒前
慢慢子发布了新的文献求助10
28秒前
内向翰完成签到,获得积分10
29秒前
30秒前
碧蓝的睫毛完成签到,获得积分10
30秒前
靖哥哥发布了新的文献求助30
30秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Neuromuscular and Electrodiagnostic Medicine Board Review 1000
こんなに痛いのにどうして「なんでもない」と医者にいわれてしまうのでしょうか 510
The First Nuclear Era: The Life and Times of a Technological Fixer 500
Unusual formation of 4-diazo-3-nitriminopyrazoles upon acid nitration of pyrazolo[3,4-d][1,2,3]triazoles 500
岡本唐貴自伝的回想画集 500
Distinct Aggregation Behaviors and Rheological Responses of Two Terminally Functionalized Polyisoprenes with Different Quadruple Hydrogen Bonding Motifs 450
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3671619
求助须知:如何正确求助?哪些是违规求助? 3228325
关于积分的说明 9779523
捐赠科研通 2938636
什么是DOI,文献DOI怎么找? 1610158
邀请新用户注册赠送积分活动 760547
科研通“疑难数据库(出版商)”最低求助积分说明 736093