化学
重氮
激进的
催化作用
光催化
氢原子
光化学
碳原子
密度泛函理论
碳纤维
组合化学
药物化学
有机化学
计算化学
群(周期表)
复合材料
材料科学
复合数
烷基
作者
Qian Wang,Jiang Liu,Haibo Mei,Romana Pajkert,Mira Keßler,Gerd-Volker Röschenthaler,Jianlin Han
标识
DOI:10.1021/acs.orglett.2c03268
摘要
A Ru-catalyzed reaction of difluoroalkyl diazo compounds with Hantzsch ester under visible light to achieve the formation of α-fluorovinylphosphonates via a radical process has been developed. Mechanistic experiments and density functional theory calculations reveal that the generation of a carbon radical is directly through the hydrogen atom transfer (HAT) by Hantzsch ester. This system represents the first example of generation of carbon radicals from diazo compounds via Hantzsch-ester-assisted HAT and also demonstrates a new radical-involved pathway for the difluoroalkyl diazo compounds.
科研通智能强力驱动
Strongly Powered by AbleSci AI