作者
Naoaki Onishi,Kazuaki Kaitani,Yoshihisa Nakagawa,Koichi Inoue,Atsushi Kobori,Yuko Nakazawa,Tomoya Ozawa,Toshiya Kurotobi,Itsuro Morishima,Fumiharu Miura,Tetsuya Watanabe,Masaharu Masuda,Masaki Naito,Hajime Fujimoto,Taku Nishida,Yoshio Furukawa,Takeshi Shirayama,M Tanaka,Katsunori Okajima,Takenori Yao,Yasuyuki Egami,Kazuhiro Satomi,Takashi Noda,Koji Miyamoto,Tetsuya Haruna,Yukei Higashi,Makoto Ito,Minoru Horie,Kengo Kusano,Wataru Shimizu,Shiro Kamakura,Yukiko Shimizu,Koji Hanazawa,Toshihiro Tamura,Chisato Izumi,Takeshi Morimoto,Takeshi Kimura,Satoshi Shizuta,East-Af Investigators
摘要
Abstract Background The relationship between the timing of the first early recurrence and late recurrence after a single catheter ablation procedure for atrial fibrillation is controversial. Methods The Efficacy of Short-Term Use of Antiarrhythmic Drugs After Catheter Ablation for Atrial Fibrillation trial followed 2038 patients who underwent radiofrequency catheter ablation for atrial fibrillation. Results Of the patients, 907 (45%) had early recurrences within 90 days after the initial ablation. We divided these patients into two groups according to the timing of the first early recurrence episode, namely the ER1 group (early recurrence during the early phase; 0–30 days, n = 814) and ER2 group (early recurrence during the late phase; 31–90 days, n = 93). Three years after ablation, patients with early recurrences had a significantly lower event-free rate from late recurrences after a 90-day blanking period than patients without early recurrences (36.2% and 74.2%, respectively; log-rank, P Conclusion Early recurrences were strongly associated with late recurrences, especially in patients with the first recurrence episode at >1 month within the blanking period after a single ablation procedure. Therefore, these patients should undergo close observation during follow-up, when they had especially with non-paroxysmal atrial fibrillation.