立体选择性
化学
催化作用
配体(生物化学)
卤化物
钴
烷基
立体化学
偶联反应
组合化学
联轴节(管道)
有机化学
材料科学
受体
生物化学
冶金
作者
Mingjie Zeng,Changyue Yu,Yibing Wang,Jingjing Wang,Jiang Wang,Hong Liu
标识
DOI:10.1002/ange.202300424
摘要
Abstract We report a ligand‐controlled Co II ‐catalyzed C(sp 3 )−C(sp 3 ) coupling hydroalkylation for direct and β‐selective synthesis of 2‐deoxy‐C‐glycosides from glycals. This reaction proceeds by a radical pathway for alkyl halide activation and is β‐selective through ligand control. This approach may inspire the development of further stereoselective coupling reactions with potential application in the field of carbohydrates.
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