化学
路易斯酸
催化作用
有机催化
亚胺
沮丧的刘易斯对
炔烃
硅烷化
烯烃
路易斯酸催化
硅氢加成
背景(考古学)
有机化学
硼
组合化学
对映选择合成
古生物学
生物
作者
Muhammad Israr,Woo Hee Kim,Dong Hyeon Kim,Han Yong Bae
标识
DOI:10.1016/j.checat.2023.100866
摘要
In response to the growing demand for sustainable chemistry, there has been a notable surge of interest in developing efficient, metal-free, and versatile organic acid catalysts capable of facilitating the synthesis of complex valuable molecules. In this context, a silylium ion (tricoordinate, trivalent silyl cations) combined with a weakly coordinating anion as an organocatalyst could operate as a highly potent promotor in multifunctional transformations. We summarize the recent developments of silylium Lewis acid catalysis, mainly induced by trityl tetrakis(pentafluorophenyl)borate ([Ph3C]+[B(C6F5)4]–) as a highly efficient catalytic precursor. The neutral, moisture-tolerant, bench-stable, metal-free salt could successfully catalyze diverse categorized transformations such as (1) hydrosilylation of alkene and alkyne, (2) reduction of carbonyl and imine, (3) carbon–fluorine bond activation, and (4) carbon–carbon bond formation. Concise mechanistic elaborations on the appeared reactions are discussed.
科研通智能强力驱动
Strongly Powered by AbleSci AI